08h30

Accueil des participants & Installation des posters

09h00

Introduction Delphine ALLORGE, Benoit DEPREZ, Christophe FURMAN

09h15

Dr Christel Menet,

Chief Scientific Officer, Confo therapeutics.

The discovery of CFTX-1554 as an inhibitor of the angiotensin II type 2 receptor, a clinically validated target for the treatment of neuropathic pain

10h15

Pierre SIEROCKI, Overcoming the limitations of peptidic scaffolds using KTGS: discovery of the 1st druglike & selective ERAP2 inhibitors, U1177 - Drugs and Molecules for Living Systems

10h35

Pause Café 

11h00 

Morgane RIVOAL, Development of NOD1 - RIPK2 selective inhibitors for the treatment of liver ischemia - reperfusion injury, Infinite Inserm U1286 

11h20

Nina COMPAGNE, Pyridylpiperazines as efflux pump inhibitors to overcome antimicrobial resistance, U1177 - Drugs and Molecules for Living Systems

11h40

Clément VIGIER, Elucidation of mechanism of action and target of alkylated fluoroquinolones presenting activity on Mycobacterium tuberculosis, using click-chemistry coupled to MS analysis, U1177 - Drugs and Molecules for Living Systems

12h00

Lunch & session posters

13h45

Lisa BONIN, Modulation of benzothiophene and 2,4-thiazolidinedione derivatives identified as new RAGE ligands via molecular docking and ELISA assays, UMR 6014 & FR3038, JUNIA 

14h05

Fatima Zahra CHAIBI, Identification and optimization of new covalent reversible inhibitors of the 3CL protease of SARS-CoV-2, U1177 - Drugs and Molecules for Living Systems

14h25

Benjamin GRAIN, Fast-SEA: modifying proteins in the nanomolar concentration range with a chemoselective thioester-based ligation reaction, U1019 - UMR 9017 - CIIL

14h45

Doriane HENRY, The transrepressive activity of PPARα induced by pemafibrate in the liver is sufficient to reduce atherosclerosis development in LDLr deficient mice, U1011-EGID

15h05

Pause Café

15h25

Francesca RUGGIERI, A Three-step Process to Isolate Large Quantities of Bioactive Sesquiterpene Lactones from Chicorium intybus L. Roots, U1177 - Drugs and Molecules for Living Systems

15h45

Alice BOULLOY, Small Molecules Aborting Resistance (SMARt) as a means to overcome antibiotic resistance in Tuberculosis, U1177 - Drugs and Molecules for Living Systems

16h05

Pr Dimitris Georgiadis,

Université Nationale et Kapodistrienne d'Athènes, Grèce,

Phosphinic Peptides in Medicinal Chemistry

17h05

Délibération du Jury

17h15

Remise de prix (Poster & Conférence)