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ORGANISATION > Member teams > INSERM U1008

INSERM U1008

Director : Pr. Juergen Siepmann

Lille 2 University

Lab Web page : http://u1008.univ-lille2.fr/

Research themes : Controlled drug release, mechanisms, microparticles, implants, pellets, tablets, biomaterials, functionalization.

Technical expertise : Optimization and characterization of pharmaceutical dosage forms for oral (pellets, tablets), parenteral (implants, microparticles) or nasal application and biomaterials (drug eluting stents, bone implants, in-situ forming implants).

5 Recent publications :

  • Siepmann, F.; Eckart, K.; Maschke, A.; Kolter, K.; Siepmann, J., Modeling drug release from PVAc/PVP matrix tablets, Journal of Controlled Release 2010, 141, 216-222.
  • Haulon, S.; Amiot, S.; Magnan, PE.; Becquemin, J.P.; Lermusiaux, P.; Koussa, M.; Batt, M.; Favre, J.P., An analysis of the French multicentre experience of fenestrated aortic endografts: medium-term outcomes, Ann Surg. 2010, 251, 357-362.
  • Muschert, S.; Siepmann, F.; Leclercq, B.; Carlin, B.; Siepmann, J., Prediction of drug release from ethylcellulose coated pellets, Journal of Controlled Release 2009, 135, 71-79.
  • Siepmann, F.; Herrmann, S.; Winter, G.; Siepmann, J., A novel mathematical model quantifying drug release from lipid implants, Journal of Controlled Release 2008, 128, 233-240.
  • Siepmann, F.; Siepmann, J.; Walther, M.; MacRae, RJ.; Bodmeier, R., Polymer blends for controlled release coatings, Journal of Controlled Release 2008, 125, 1-15.

Contacts :

Prof. Dr. Juergen SIEPMANN (U 1008 director)
Prof. Dr. Elisabeth DELCOURT-DEBRUYNE
Prof. Dr. Joël FERRI
Prof. Dr. Stéphan HAULON
Dr. Frédéric HILDEBRAND
Dr. Nicolas BLANCHEMAIN
Dr. Fançois BOSCHIN
Dr. Marie-Pierre FLAMENT
Dr. Youness KARROUT
Dr. Susanne MUSCHERT
Dr. Gwénaël RAOUL
Dr. Florence SIEPMANN


Microscopic pictures of coated- minigranules


Microscopic prictures of biodegradable microparticules


Microscopic and macroscopic pictures of lipidic implants


Vascular prostheses